Neonatal & Pediatric Dilutions (IV Room 2024 USP 797)
Source: Neonatal and Pediatric Dilutions IV room 2024 797 document – consolidated for clinical reference.
For patients < 11 kg: Dispense in a syringe.
For patients > 11 kg: Dispense in a bag (25 to 50 mL, minimum 25 mL).
Verify every dose before compounding and follow hospital policy for beyond use dating.
Bulk product: Dilute in syringe or empty flex container, whichever is appropriate. Protect from light storage, where required.
Patient-specific doses: Dispense in a syringe (minimum 5 mL) or empty flex container for doses > 50 mL. Maximum expiration is 24 hours or the documented BUD, whichever is shorter.
Patient-specific doses: Dispense in a syringe (minimum 5 mL) or empty flex container for doses > 50 mL. Maximum expiration is 24 hours or the documented BUD, whichever is shorter.
| Drug name | Reconstitution | Dilution Use D5W unless specified |
Final Conc. | Beyond Use Date Bulk Product |
auxiliary Labels | Comments |
| Bulk product: Dilute in syringe or empty flex container, whichever is appropriate. Protect from light storage, where required. Patient specific dose syringe: Dispense dose in syringe (minimum 5 mL) or empty flex container (Doses > 50 mL) Maximum 24 hour expiration – or BUD, whichever is shorter. |
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| Acetaminophen IVPB |
1000 mg/100 mL Premixed bottle |
Withdraw dose from premixed bottle | 10 mg/mL | Bulk: 84 hr RT * Transferred: RT: 24 hr |
* If punctured MFG bottle left in IV hood | |
| Acetazolamide IVPB |
500 mg + 5 mL SWFI | 5 mL (500 mg) + 15 mL NS | 25 mg/mL | Frig: 24 hr | Refrigerate | |
| Acetylcysteine IVPB |
6 gm/30 mL | Follow individual patient label | Variable | RT: 24 hr | Colorless to slight pink or purple | |
| Acyclovir IVPB |
500 mg/10 mL 1000 mg/20 mL |
10 mL (500 mg) + 90 mL 20 mL (1000 mg) + 180 mL |
5 mg/mL | RT: 4 days | Do not refrigerate | Colorless to yellow |
| Alprostadil IVPB |
500 mcg /mL | 1 mL (500 mcg) + 49 mL (NS or D5) | 10 mcg/mL | Bulk: 10 days Frig (protect from light) RT: 24 hr |
Refrigerate | |
| Albumin 25% IVPB |
12.5 gm/50 mL | Withdraw dose from premixed vial Avoid shaking |
250 mg/mL | RT: 24 hr | Avoid shaking | Clear, straw, amber, or dark-brown |
| Albumin 5% IVPB |
12.5 gm/250 mL | Withdraw dose from premixed vial Avoid shaking |
50 mg/mL | RT: 24 hr | Avoid shaking | Clear, straw, amber, or dark-brown |
| Amikacin IVPB |
500 mg/2 mL | 2 mL (500 mg) + 48 mL | 10 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | Colorless, pale yellow or straw |
| Aminocaproic acid IVPB |
5 gm/20 mL | 8 mL (2000 mg) + 92 mL 20 mL (5000 mg) + 230 mL |
20 mg/mL | RT: 4 days | ||
| Aminophylline IVPB |
250 mg/10 mL | 10 mL (250 mg) + 40 mL 20 mL (500 mg) + 80 mL |
5 mg/mL | Bulk:2 days Frig RT: 24 hr |
Refrigerate | Yellow after 24 hr |
| Amiodarone Continuous infusion |
150 mg/100 mL Premixed bag |
Dispense entire premixed bag Avoid shaking |
1.5 mg/mL | NA | Avoid shaking | Light protection not required 0.2 micron filter |
| Amiodarone Continuous infusion |
150 mg/3 mL 900 mg/18 mL |
7.5 mL (375 mg) + 242.5 mL (Use PVC-free or glass 250 mL D5W bag) |
1.5 mg/mL | RT: 24 hr | Avoid shaking | Light protection not required 0.2 micron filter |
| Ampicillin IVP |
250 mg + 2.4 mL SWFI 500 mg + 4.8 mL SWFI |
No further dilution | 100 mg/mL | RT: 1 hr | For immediate use | Colorless, pale yellow |
| Ampicillin IVPB |
2 GM + 15 mL SWFI | Withdraw entire vial contents (2 gm) QS to 40 mL SWFI |
50 mg/mL | Bulk: 24 hr Frig RT: 6 hr |
Refrigerate | Colorless, pale yellow |
| Ampicillin IVPB |
1 GM + 10 mL SWFI | Withdraw entire vial contents (1 gm) QS to 40 mL NS |
25 mg/mL | Bulk: 48 hr RT: 30 hr |
Refrigerate | |
| Ampicillin/sulbactam IVPB |
3 GM + 8 mL SWFI | Withdraw entire vial contents (3 gm) QS to 80 mL NS |
25 mg/mL (ampicillin) | Bulk: 3 days Frig RT: 24 hr |
Refrigerate | Unasyn (amp/sulbactam) conc: 37.5 mg/mL |
| Azithromycin IVPB |
500 mg + 5 mL SWFI | Withdraw entire vial contents (500 mg) QS to 250 mL (NS or D5W) |
2 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | |
| Aztreonam IVP |
1 gm + 9 mL SWFI | No further dilution | 100 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | Colorless, straw or pale yellow. Dry powder may yellow |
| Aztreonam IVPB |
2 gm + 15mL SWFI | Withdraw entire vial contents (2 gm) QS to 40 mL SWFI |
50 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | Colorless, straw or pale yellow. Dry powder may yellow |
| Bumetanide Ped ≥ 5 kg Continuous infusion |
1 mg/4mL | Withdraw undiluted drug into syringe or empty bag total volume depends infusion rate | 0.25 mg/mL | RT: 4 days | ||
| Bumetanide Neo < 5 kg | 1 mg/4 mL | 4.8 mL (1.2 mg) + 45.2 mL | 24 mcg/mL | RT: 3 days | ||
| Bulk product: Dilute in syringe or empty flex container, whichever is appropriate. Protect from light storage, where required. Patient specific dose syringe: Dispense dose in syringe (minimum 5 mL) or empty flex container (Doses > 50 mL) Maximum 24 hour expiration – or BUD, whichever is shorter. |
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| Caffeine citrate IVPB |
60 mg /3 mL | Withdraw dose from premixed | 20 mg/mL | RT: 4 days | ||
| Calcium chloride IVPB |
1000 mg/10 mL | 10 mL (1000mg) + 40 mL | 20 mg/mL | RT: 24 hr | ||
| Calcium gluconate IVPB |
1000 mg/10 mL | 10 mL (1000mg) + 10 mL 20 mL (2000mg) + 20 mL |
50 mg/mL | RT: 24 hr | ||
| Cefazolin IVP |
1 gm + 9.5 mL SWFI | No further dilution | 100 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | |
| Cefazolin IVPB |
1 gm + 10 mL SWFI | Withdraw entire vial contents (1 gm) QS to 20 mL |
50 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | |
| Cefepime IVPB |
2 gm + 15 mL SWFI | Withdraw entire vial contents (2gm) QS to 40 mL SWFI |
50 mg/mL | Bulk: 7 days Frig 20 hr RT |
Refrigerate | Colorless to amber |
| Cefotaxime IVP |
500 mg + 4.8 mL SWFI 1 gm + 9.6 mL SWFI 2 gm + 18.9 mL SWFI |
No further dilution | 100 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | Off white, pale yellow or amber |
| Cefotaxime IVPB |
2 gm + 10 mL SWFI | Withdraw entire vial contents (2 gm) QS to 40 mL |
50 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | Off white, pale yellow or amber |
| Cefoxitin IVP |
1 gm + 9.5 mL SWFI 2 gm + 19 mL SWFI |
No further dilution | 100 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | Colorless to light amber |
| Cefoxitin IVPB |
2 gm + 15 mL SWFI | Withdraw entire vial contents (2gm) QS to 40 mL |
50 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | Colorless to light amber |
| Ceftazidime IVP |
Vent prior to reconstitution * 1 gm + 9.2 mL SWFI 2 gm + 18.5 mL SWFI |
No further dilution | 100 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | * due to carbon dioxide gas bubble formation Yellow, amber May darken upon storage |
| Ceftazidime IVPB |
Vent prior to reconstitution * 2 gm + 15 mL SWFI |
Withdraw entire vial contents (2 gm) QS to 40 mL |
50 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | * due to carbon dioxide gas bubble formation Yellow, amber May darken upon storage |
| Ceftriaxone IVP Ped (>11 yrs old) |
250 mg + 2.4 mL SWFI 500 mg + 4.8 mL SWFI 1 gm + 9.6 mL SWFI 2 gm + 19.2 mL SWFI |
No further dilution | 100 mg/mL | Bulk: 10 days Frig 2 days RT |
Refrigerate | Light yellow, amber |
| Ceftriaxone IVPB |
2 gm + 15 mL SWFI | Withdraw entire vial contents (2 gm) QS to 40 mL |
50 mg/mL | Bulk: Frig 10 days RT: 2 days |
Refrigerate | Light yellow, amber |
| Ceftriaxone IVPB |
1 gm + 10 mL SWFI | Withdraw entire vial contents (1 gm) QS to 40 mL NS |
25 mg/mL | Bulk: 10 days Frig RT: 2 days |
Refrigerate | Light yellow, amber |
| Cefuroxime IVP |
750 mg + 7 mL SWFI | No further dilution | 100 mg/mL | Bulk: 48 hr Frig RT: 24 hr |
Refrigerate | |
| Cefuroxime IVPB |
750 mg + 7 mL SWFI | Withdraw entire vial contents (750mg) QS to 15 mL |
50 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | |
| Chlorothiazide IVPB |
500 mg + 18 mL SWFI | 18 mL (500 mg) + 32 mL NS | 10 mg/mL | RT: 24 hr | ||
| Ciprofloxacin IVPB |
400 mg/200 mL Premixed bag |
Withdraw dose from premixed bag | 2 mg/mL | Bulk: 7 days Frig RT: 24 hr |
Refrigerate | Light protection not required |
| Bulk product: Dilute in syringe or empty flex container, whichever is appropriate. Protect from light storage, where required. Patient specific dose syringe: Dispense dose in syringe (minimum 5 mL) or empty flex container (Doses > 50 mL) Maximum 24 hour expiration – or BUD, whichever is shorter. |
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| Cisatracurium IVPB |
20 mg/10 mL | No further dilution | 2 mg/mL | 7 days Frig 30 hr RT |
Colorless, yellow or greenish-yellow | |
| Clindamycin IVPB |
900 mg/6 mL | 6 mL (900 mg) + 84 mL | 10 mg/mL | Bulk: 10 days Frig RT: 4 days |
Refrigerate | |
| Clindamycin IVPB |
Premixed presentations 300 mg/50 mL (6 mg/mL) NS 600 mg/50 mL (12 mg/mL) NS or D5W 900 mg/50 mL (18 mg/mL) NS or D5W 900 mg/100 mL (9 mg/mL) NS |
Draw up appropriate dose following labeling instructions. May withdraw entire contents into 50 mL syringe with syringe adaptor and store in the refrigerator as bulk solution for syringe doses. |
Varies due to drug shortage. | Bulk: 10 days Frig RT: 4 days |
Refrigerate | |
| Daptomycin IVP |
500 mg + 10 mL NS Avoid shaking |
No further dilution | 50 mg/mL | Frig: 7 days RT: 12 hr | Refrigerate Avoid shaking |
|
| Daptomycin IVPB |
500 mg + 10 mL NS Avoid shaking |
10 mL (500 mg) + 15 mL NS 20 mL (1000 mg) + 30 mL NS |
20 mg/mL | Frig: 7 days RT: 12 hr | Refrigerate Avoid shaking |
|
| Dexamethasone IVP Neo |
10 mg/mL | 1 mL (10mg) + 9 mL NS | 1 mg/mL | Frig: 7 days RT: 24 hr | ||
| Dexamethasone IVP Ped |
10 mg/mL | Withdraw dose from premixed vial | 10 mg/mL | Frig: 7 days RT: 24 hr | ||
| Dexmedetomidine Continuous infusion |
200 mcg/2 mL | 2mL (200 mcg) + 48 mL NS | 4 mcg/mL | RT: 24 hr | ||
| Digoxin IVP Neo |
100 mcg/mL | 1 mL (100mcg) + 9 mL NS | 10 mcg/mL | Frig: 48 hr | Refrigerate | |
| Digoxin IVP Ped |
100 mcg/mL | Withdraw dose from premixed vial | 100 mcg/mL | RT: 24 hr | ||
| Digoxin Immune fab IVPB Neo |
40 mg + 4 mL SWFI | 4 mL (40 mg) + 36 mL NS | 1 mg/mL | Frig: 4 hr RT: 1 hr |
Refrigerate | |
| Digoxin Immune fab IVPB Ped |
40 mg + 4 mL SWFI | No further dilution | 10 mg/mL | Frig: 4 hr RT: 1 hr |
Refrigerate | |
| Diltiazem Continuous infusion |
125 mg/25 mL | 25 mL (125 mg) + 100 mL NS | 1 mg/mL | Frig: 7 days RT: 48 hr | Refrigerate | |
| Dobutamine Continuous infusion |
250 mg/250 mL Premixed bag |
Dispense premixed bag | 1 mg/mL | NA | Colorless, pale yellow, straw or pink |
|
| Dopamine Ped Neo Continuous infusion |
400 mg/250 mL Premixed bag |
Dispense premixed bag | 1600 mcg/mL | NA | ||
| Doxycycline IVPB |
100 mg + 10 mL SWFI | Withdraw entire vial contents (100 mg) QS to 100 mL |
1 mg/mL | Frig: 7 days RT: 48 hr | Refrigerate Protect from light | |
| Enalaprilat IVP/IVPB |
1.25 mg/mL | 1 mL (1.25mg) + 49 mL NS | 25 mcg/mL | RT: 24 hr | ||
| Epinephrine Neo Continuous infusion |
1mg /mL | 5 mL (5 mg) + 245 mL | 20 mcg/mL | Frig: 7 days RT: 30 hr Protect from light | Colorless to slight yellow Unacceptable: Pink to brown Light protection bulk only |
|
| Epinephrine Ped Continuous infusion |
1 mg /mL | 15 mL (15mg) + 235 mL | 60 mcg/mL | Frig: 7 days RT: 30 hr Protect from light | Colorless to slight yellow Unacceptable: Pink to brown Light protection bulk only |
|
| Ertapenem IVPB Ped |
1 gm + 10 mL SWFI | Withdraw entire vial contents (1 gm) QS to 50 mL NS |
20 mg/mL | Frig: 5 days RT: 20 hr | Refrigerate | |
| Esmolol Continuous infusion |
2500 mg/250 mL Premixed bag |
Dispense premixed bag | 10 mg/mL | RT: 24 hr | Colorless, yellow | |
| Bulk product: Dilute in syringe or empty flex container, whichever is appropriate. Protect from light storage, where required. Patient specific dose syringe: Dispense dose in syringe (minimum 5 mL) or empty flex container (Doses > 50 mL) Maximum 24 hour expiration – or BUD, whichever is shorter. |
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| Famotidine IVP |
20 mg/2mL – PF only | 2 mL (20 mg) + 8 mL | 2 mg/mL | Frig: 10 days RT: 4 days |
Refrigerate | |
| Famotidine IVPB |
20 mg/50mL Premixed bag |
Withdraw dose from premixed bag | 0.4 mg/mL | Frig: 10 days RT: 4 days |
Refrigerate | |
| Famotidine | 20 mg/2 mL PF | 4 mL (40 mg) + 6 mL NS | 4 mg/mL | Frig: 10 days RT: 4 days |
Refrigerate | |
| Fentanyl IVP Neo Continuous |
1000 mcg/20 mL SDV | 20 mL (1000 mcg) + 80 mL | 10 mcg/mL | Frig: 10 days RT: 4 days |
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| Fluconazole IVPB |
200 mg/100 mL Premixed bag |
Withdraw dose from premixed bag | 2 mg/mL | Frig: 7 days RT: 48 hr | ||
| Fomepizole IVPB | 1.5 gm/1.5 mL | 1.5 mL (1.5 gm) + 58.5 mL | 25 mg/mL | RT: 24 hr | Colorless, yellow. | |
| Fosphenytoin IVPB |
100 mg PE / 2 mL Premixed |
Withdraw specific dose and dilute 1:1 For every 1 mL of drug add 1 mL of diluent |
25 mg PE/mL | Frig: 7 days RT: 24 hr | Colorless, pale yellow. No crystals or precipitates |
|
| Furosemide IVPB Neo |
100 mg/10 mL | 10mL (100 mg) + 90 mL | 1 mg/mL | RT: 24 hr | Colorless. Unacceptable: yellow Light protection not required |
|
| Furosemide IVPB Ped |
10 mg/mL | Withdraw dose from premixed vial | 10 mg/mL | RT: 24 hr | Colorless. Unacceptable: yellow Light protection not required |
|
| Gentamicin | 20 mg/2 mL PF | 2 mL (20 mg) + 8 mL NS | 2 mg/mL | Frig: 10 days RT: 24 hr |
Refrigerate | Colorless, slight yellow. |
| Gentamicin | 40 mg/mL (parabens) acceptable in neo/peds when PF not available | 1 mL (40 mg) + 19 mL NS | 2 mg/mL | Frig: 10 days RT: 24 hr |
Refrigerate | Colorless, slight yellow. |
| Gentamicin MPF Doses < 5 mg |
20 mg/2 mL PF | Withdraw specific dose and dilute 1:1 For every 1 mL of drug add 1 mL of diluent |
5 mg/mL | Frig: 10 days RT: 24 hr |
Refrigerate | Colorless, slight yellow. |
| Gentamicin MPF Neo/Ped IVPB |
20 mg/2 mL PF | Withdraw dose from premixed vial | 10 mg/mL | Frig: 10 days RT: 24 hr |
Refrigerate | Colorless, slight yellow. |
| Gentamicin Peds IVPB |
400 mg / 10 mL Contains preservatives |
10 mL (400 mg) + 30 mL | 10 mg/mL | Frig: 10 days RT: 24 hr |
Refrigerate | Colorless, slight yellow. |
| Glucagon IVP | 1 mg + 1 mL SWFI (diluent provided) |
No further dilution | 1 mg/mL | Frig: 48 hr RT: 24 hr | ||
| Glucagon Cont. infusion |
1 mg + 1 mL SWFI (diluent provided) |
5 mL (5mL) + 45 mL 10 mL (10 mg) + 90 mL |
0.1 mg/mL | Frig: 48 hr RT: 24 hr | ||
| Glucagon Cont. infusion |
1 mg + 1 mL SWFI (diluent provided) |
2 mL (2mg) + 98 mL | 0.02 mg/mL | Frig: 48 hr RT: 24 hr | ||
| Heparin Continuous infusion |
100 units/mL Premixed 25,000 units/250 mL |
Dispense Premixed bag | 100 units/mL | |||
| Hydrocortisone sodium succinate |
100 mg + 2 mL SWFI | Withdraw entire vial contents (100 mg) QS to 10 mL NS |
10 mg/mL | Frig: 7 days RT: 24 hr | ||
| Hydromorphone Neo Continuous infusion |
2 mg/mL SDV | 3 mL (6 mg) + 27 mL | 0.2 mg/mL | RT: 2 days | ||
| Hydromorphone Neo Continuous infusion |
1 mg/mL SDV | 10 mL (10 mg) + 40 mL | 0.2 mg/mL | RT: 2 days | ||
| Hydromorphone Ped Continuous infusion |
2 mg/mL SDV | (12.5 ml) 25 mg + 25 mL | 1 mg/mL | RT: 2 days | ||
| Hydromorphone Ped Continuous infusion |
1 mg/mL SDV | (25 mL) 25 mg + 25 mL | 1 mg/mL | RT: 2 days | ||
| Bulk product: Dilute in syringe or empty flex container, whichever is appropriate. Protect from light storage, where required. Patient specific dose syringe: Dispense dose in syringe (minimum 5 mL) or empty flex container (Doses > 50 mL) Maximum 24 hour expiration – or BUD, whichever is shorter. |
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| Insulin regular Ped Continuous infusion |
1000 units/10 mL 300 units/ 3 mL |
10 mL (100 units) add NS enough to make total volume 100 mL | 1 unit/mL | RT: 24 hr | ||
| Insulin regular Neo Continuous infusion |
1000 units/10 mL 300 units/ 3 mL |
0.1 mL (10 units) add NS enough to make total volume 100 mL | 0.1 unit/mL | RT: 24 hr | ||
| Ketamine Continuous infusion |
200 mg/20 mL | 10 mL (100 mg) + 90 mL | 1 mg/mL | Frig: 7 days RT: 24 hr | Colorless, yellow. May darken with light exposure |
|
| Ketamine Continuous infusion |
500 mg/10 mL | 5 mL (250 mg) + 245 mL | 1 mg/mL | Frig: 7 days RT: 24 hr | Colorless, yellow. May darken with light exposure |
|
| Ketamine Continuous infusion |
500 mg/10 mL | 10 mL (500 mg) + 240 mL | 2 mg/mL | Frig: 7 days RT: 24 hr | Colorless, yellow. May darken with light exposure |
|
| Ketamine IVP |
500 mg/10 mL | 10 mL (500 mg) + 40 mL | 10 mg/mL | Frig: 7 days RT: 24 hr | Colorless, yellow. May darken with light exposure |
|
| Labetolol Continuous infusion |
100 mg/20 mL | 20 mL (100 mg) + 80 mL | 1 mg/mL | RT: 24 hr | ||
| Labetolol IVP |
100 mg/20 mL | Withdraw dose from premixed vial | 5 mg/mL | RT: 24 hr | ||
| Lacosamide IVPB |
200 mg/20 mL | Withdraw specific dose and dilute 1:1 For every 1 mL of drug add 1 mL of diluent |
5 mg/mL | RT: 24 hr | ||
| Levetiracetam IVPB |
500 mg/5 mL | 5 mL (500 mg) + 45 mL | 10 mg/mL | RT: 24 hr | Colorless | |
| Lidocaine Continuous infusion |
2000 mg/500 mL Premixed bag |
Dispense premixed bag | 4 mg/mL | |||
| Linezolid IVPB |
600 mg/300 mL Premixed bag |
Withdraw dose from premixed bag | 2 mg/mL | Frig: 7 mag RT: 24 hr | Yellow, may darken over time | |
| Lorazepam IVP |
2 mg/mL Premixed |
1 mL (2 mg) + 19 mL | 0.1 mg/mL | RT: 24 hr | ||
| Magnesium sulfate IVPB |
2 gm/50 mL Premixed bag |
Withdraw dose from premixed bag | 40 mg/mL | Frig: 10 days RT: 4 days |
||
| Magnesium sulfate IVPB – fluid restricted |
5 gm/10 mL | 4 mL (2000 mg) + 6 mL SWFI | 200 mg/mL | Frig: 10 days RT: 4 days |
||
| Mannitol 20% IVPB, Continuous |
100 gm/500 mL Premixed bag |
IVPB: Withdraw dose from premixed bag Continuous: dispense premixed bag |
0.2 gm/mL | RT: 24 hr | Do not refrigerate | 1.2 micron filter |
| Meropenem IVP, IVPB |
500 mg + 5 mL SWFI | Withdraw entire vial contents (500 mg) QS to 10 mL SWFI |
50 mg/mL | Frig: 13 hr RT: 3 hr | Refrigerate | Colorless, yellow |
| Methylprednisolone sodium succinate |
40 mg + 1 mL SWFI | 1 mL + 3 mL NS | 10 mg/mL | Frig: 10 days RT: 48 hr |
Colorless | |
| Methylprednisolone sodium succinate |
40 mg + 1 mL SWFI | 1 mL (40 mg) + 9 mL NS 2 mL (80 mg) = 18 mL NS |
4 mg/mL | Bulk: 10 days RT:48 hr |
Given by RN direct IV push from syringe over 30 seconds to 1 min | |
| Metoclopramide IVP Doses < 10 mg |
10 mg/2mL | 2 mL + 8 mL NS | 1 mg/mL | RT: 24 hr | Colorless | |
| Metoclopramide IVP Doses ≥ 10 mg |
10 mg/2mL | Withdraw dose from premixed vial | 5 mg/mL | RT: 24 hr | ||
| metroNIDAZOLE IVPB |
500 mg/100 mL Premixed bag |
Withdraw dose from premixed bag | 5 mg/mL | RT: 48 hr Protect from light |
Do not refrigerate | Light protection not required |
| Bulk product: Dilute in syringe or empty flex container, whichever is appropriate. Protect from light storage, where required. Patient specific dose syringe: Dispense dose in syringe (minimum 5 mL) or empty flex container (Doses > 50 mL) Maximum 24 hour expiration – or BUD, whichever is shorter. |
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| Micafungin IVPB |
100 mg + 5 mL NS Avoid shaking |
Withdraw entire vial contents (100 mg) QS to 100 mL |
1 mg/mL | Frig: 7 days RT: 24 hr Protect from light | Refrigerate Protect from light | Avoid shaking |
| Midazolam Neo Continuous infusion |
50 mg/10 mL | 20 mL (100 mg) + 80 mL | 1 mg/mL | RT: 48 hrs | ||
| Midazolam Neo Continuous infusion |
50 mg/10 mL | 10 mL (50 mg) + 90 mL | 0.5 mg/mL | RT: 48 hr | ||
| Milrinone Continuous infusion |
20 mg/ 100 mL Premixed bag |
Dispense premixed bag | 200 mcg/mL | Colorless, pale yellow. | ||
| Morphine Ped continuous |
1 mg/mL Premixed syringe |
Dispense premixed PCA | 1 mg/mL | |||
| Morphine Neo continuous |
10 mg/mL | 1 mL (10 mg) + 99 mL | 0.1 mg/mL | RT: 24 hr | ||
| Naloxone Continuous infusion |
0.4 mg/mL | 1 mL (0.4 mg) + 49 mL 2 mL (0.8 mg) + 98 mL |
8 mcg/mL | RT: 24 hr | ||
| Naloxone Continuous infusion |
2 mg/ 2 mL | 10 mL (10 mg) + 90 mL 20 mL (20 mg) + 180 mL |
100 mcg/mL | RT: 24 hr | ||
| Nicardipine Continuous infusion |
20 mg/200 mL Premixed bag |
Dispense premixed bag | 0.1 mg/mL | RT: 24 hr | * Caution: dextrose and sodium chloride premixes look similar | |
| Nitroglycerine Continuous infusion |
25 mg/250 mL Premixed bottle |
Dispense premixed bottle | 100 mcg/mL | RT: 24 hr | Dispense with nitroglycerin tubing | |
| Norepinephrine Continuous infusion |
4 mg/4 mL | 2 mL (2 mg) + 98 mL 4 mL (4 mg) + 196 mL 10 mL (10 mg) + 490 mL |
20 mcg/mL | Frig: 10 days | Unacceptable: darkened Light protection not required |
|
| Octreotide Continuous infusion |
100 mcg/mL | 2 mL (200 mcg) octreotide + 38 mL | 5 mcg/mL | RT: 24 hr | Light protection not required Note: various /ampule strengths may look alike. |
|
| Octreotide Continuous infusion |
500 mcg/mL | 1 mL (500 mcg) octreotide + 99 mL | 5 mcg/mL | RT: 24 hr | Light protection not required Note: various /ampule strengths may look alike. |
|
| Octreotide Continuous infusion |
100 mcg/mL | 2 mL (200 mcg) + 18 mL | 10 mcg/mL | RT: 24 hr | Light protection not required Note: various /ampule strengths may look alike. |
|
| Octreotide Continuous infusion |
500 mcg/mL | 1 mL (500 mcg) octreotide + 49 mL | 10 mcg/mL | RT: 24 hr | Light protection not required Note: various /ampule strengths may look alike. |
|
| Ondansetron IVP Doses ≤ 8 mg |
4 mg/2 mL | Withdraw dose from premixed vial | 2 mg/mL | Frig: 7 days RT: 24 hr | ||
| Ondansetron IVPB Doses > 8 mg |
4 mg/2 mL | Withdraw specific dose and dilute 1:1 For every 1 mL of drug add 1 mL of diluent |
1 mg/mL | Frig: 7 days RT: 24 hr | ||
| Oxacillin IVP |
1 gm + 9.6mL SWFI 2 gm + 18.8 mL SWFI |
No further dilution | 100 mg/mL | Frig: 7 days RT: 24 hr | ||
| Oxacillin IVPB |
2 gm + 15 mL SWFI | Withdraw entire vial contents (2 gm) QS to 40 mL |
50 mg/mL | Frig: 7 days RT: 24 hr | ||
| Penicillin G potassium IVPB |
5 million units + 8 mL SWFI |
Withdraw entire vial contents (5 million) QS to 50 mL |
100,000 units /mL | Frig: 7 days RT: 24 hr | ||
| PHENobarbital Neo IVPB |
65 mg/mL | 1 mL (65 mg) + 5.5 mL NS | 10 mg/mL | Frig: 48 hr RT: 24 hr | ||
| Bulk product: Dilute in syringe or empty flex container, whichever is appropriate. Protect from light storage, where required. Patient specific dose syringe: Dispense dose in syringe (minimum 5 mL) or empty flex container (Doses > 50 mL) Maximum 24 hour expiration – or BUD, whichever is shorter. |
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| PHENobarbital Ped IVPB |
65 mg/mL | Withdraw dose from premixed vial | 65 mg/mL | RT: 24 hr | ||
| Phenylephrine Continuous infusion |
10 mg/mL | 0.6 mL (6 mg) + 59.4 mL NS | 0.1 mg/mL | Frig: 7 days RT: 24 hr Protect from light | Light protection not required | |
| Phenylephrine Continuous infusion |
10 mg/ml | 1 mL (10 mg) + 99 mL NS | 0.1 mg/mL | Frig: 7 days RT: 24 hr Protect from light | Light protection not required | |
| Phenylephrine Continuous infusion |
50 mg/5 mL | 2.5 mL (25 mg) + 247.5 mL NS | 0.1 mg/mL | Frig: 7 days RT: 24 hr Protect from light | Light protection not required | |
| Phenytoin IVBP |
250 mg/5mL | 5 mL (250 mg) + 45 mL NS | 5 mg/mL | RT: 4 hr | Slight discoloration 1.2 micron filter |
|
| Phenytoin IVBP |
250 mg/5mL | 10 mL (500 mg) + 90 mL NS | 5 mg/mL | RT: 4 hr | Slight discoloration 1.2 micron filter |
|
| Phenytoin IVPB |
100 mg/2mL | Withdraw dose from premixed vial | 50 mg/mL | RT: 24 hr | No filter required | |
| piperacillin/tazobactam IVPB |
4.5 gm + 18 mL SWFI | Withdraw entire vial contents (4.5 gm) QS to 80 mL |
50 mg/mL piperacillin |
Frig: 7 days RT: 24 hr | Zosyn concentration(pip/tazo): 56.25 mg/mL Dry powder white, yellow |
|
| Potassium chloride IVPB |
10 mEq/5mL 20 mEq/10 mL |
5 mL (10 mEq) + 120 mL 10 mL (20 mEq) + 240 mL |
0.08 mEq/mL | Frig: 7 days RT: 24 hr | OR follow patient specific label | |
| Potassium phosphate IVPB |
15 mMol/5 mL | 1 mL (3 mMol) + 59 mL 2 mL (6 mMol) + 118 mL 3 mL (9 mMol) + 177 mL |
0.05 mMol/mL | Frig: 7 days RT: 24 hr | OR follow patient specific label | |
| Procainamide Continuous infusion |
1000 mg/10 mL syr | 1 mL (100 mg) + 49 mL 2 mL (200 mg) + 98 mL |
2 mg/mL | Frig: 7 days RT: 24 hr | Colorless, light amber Unacceptable: darker amber |
|
| Propofol Continuous infusion |
10 mg/mL Premixed bottle |
Dispense premixed vial | 10 mg/mL | RT: 12 hr | ||
| Rocuronium Continuous Infusion |
10 mg/mL | 5 mL (50 mg) + 45 mL | 1 mg/mL | RT: 24 hr | ||
| Rocuronium IVPB |
10 mg/mL | Withdraw dose from premix vial | 10 mg/mL | RT: 24 hr | ||
| Sodium Nitroprusside Continuous |
50 mg/2mL | 1 mL (25 mg) + 249 mL | 100 mcg/mL | RT: 24 hr Protect from light |
Protect from light | Unacceptable: blue |
| Terbutaline IVPB Neo Continuous |
1 mg/mL | 10 mL (10 mg) + 90 mL NS 15 mL (15 mg) + 135 mL NS 25 mL (25 mg) + 225 mL NS |
0.1 mg/mL | Frig: 10 days RT: 4 days Protect from light |
Unacceptable: discolored solution Light protection not required |
|
| Terbutaline Ped IVPB |
1 mg/mL | 10 mL (10 mg) + 10 mL NS 25 mL (25 mg) + 25 mL NS 50 mL (50 mg) + 50 mL NS |
0.5 mg/mL | Frig: 10 days RT: 4 days Protect from light |
Unacceptable: discolored solution Light protection not required |
|
| Terbutaline Ped Continuous |
1 mg/mL | 25 mg/25 mL straight drug 50 mg/50 mL straight drug |
1 mg/mL | Frig: 10 days RT: 4 days Protect from light |
Unacceptable: discolored solution Light protection not required |
|
| Trimethoprim- Sulfamethoxazole IVPB Peds |
800mg / 160mg / 10mL | 10 mL (160 mg TMP) + 150 mL | 1 mg/mL TMP |
Bulk: RT: 24 hr | Do not refrigerate | |
| Tobramycin IVPB Neo Dose ≥10mg |
20 mg/2 mL | Withdraw dose from premixed vial | 10 mg/mL | Frig: 7 days RT: 24 hr | Refrigerate | Colorless, slight yellow. |
| Tobramycin IVPB Neo Dose <10mg |
20 mg/2 mL | Withdraw specific dose and dilute 1:1 For every 1 mL of drug add 1 mL of diluent |
5 mg/mL | Frig: 7 days RT: 24 hr | Refrigerate | Colorless, slight yellow. |
| Bulk product: Dilute in syringe or empty flex container, whichever is appropriate. Protect from light storage, where required. Patient specific dose syringe: Dispense dose in syringe (minimum 5 mL) or empty flex container (Doses > 50 mL) Maximum 24 hour expiration – or BUD, whichever is shorter. |
||||||
| Tobramycin IVPB Ped |
1200 mg/30 mL | 10 mL (400 mg) + 30 mL | 10 mg/mL | Frig: 7 days RT: 24 hr | ||
| Valproate sodium | 500 mg/5mL | 5 mL (500 mg) + 45 mL 10 mL (1000 mg) + 90 mL |
10 mg/mL | RT: 24 hr | Clear, colorless | |
| Valproate sodium | 500 mg/5mL | 10 mL (1000 mg) valproate + 10 mL | 50 mg/mL | RT: 24 hr | Clear, colorless | |
| Vancomycin IVPB |
1 gm + 20 mL SWFI | 20 mL (1 gm) + 180 mL NS | 5 mg/mL | Frig: 10 days RT: 2 days |
Refrigerate | |
| Vancomycin IVPB |
1 gm + 20 mL SWFI | 20 mL (1 gm) + 180 mL | 5 mg/mL | Frig: 10 days RT: 4 days | Refrigerate | |
| Vancomycin IVPB Fluid restricted |
1 gm + 20 mL SWFI | 20 mL (1 gm) + 80 mL | 10 mg/mL | Frig: 10 days RT: 4 days | Refrigerate | Fluid restricted or to minimize fluid delivery |
| Vasopressin Continuous infusion |
20 units/mL | 1 mL (20 units) + 19 mL = 1 unit/mL Further dilute 1 mL (1 unit) + 99mL |
0.01 unit/mL | RT: 24 hr/Frig | ||
| Vasopressin Continuous infusion |
20 units/mL | 3 mL (60 units) + 57 mL | 1 unit/mL | RT: 24 hr/Frig | ||
| Vecuronium Continuous infusion |
10 mg + 10 mL SWFI | 20 mL (20 mg) + 80 mL | 0.2 mg/mL | RT: 24 hr Protect from light |
Protect from light | |
| Vecuronium Continuous infusion |
10 mg + 10 mL SWFI | 50 mL (50 mg) + 50 mL | 0.5 mg/mL | RT: 24 hr Protect from light |
Protect from light | |
| Zidovudine IVPB |
200 mg/20 mL | 20 mL (200 mg) + 30 mL | 4 mg/mL | Frig: 7 days RT: 24 hr Protect from light | ||